Serotonin immunoreactivity is contained in one physiological cell class in the rat rostral ventromedial medulla

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Serotonin lmmunoreactivity Is Contained in One Physiological Cell Class in the Rat Rostra1 Ventromedial Medulla

Neurons in the rostra1 ventromedial medulla (RVM) are the major source of serotonergic projections to the dorsal horn. A large body of evidence implicates RVM serotonergic neurons in the modulation of spinal nociceptive transmission. Three physiological classes of RVM neurons, on, off, and neutral cells, are postulated to have different nociceptive modulatory effects on spinal nocifensor reflex...

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ژورنال

عنوان ژورنال: The Journal of Neuroscience

سال: 1994

ISSN: 0270-6474,1529-2401

DOI: 10.1523/jneurosci.14-03-01655.1994